參考文獻 1. Dean G. : Annual incidence, prevalence and mortality rates of MS in white South African born and in white immigrants to South Africa. BMJ 1967;2:724-730. 2. Paty DW, Ebers GC (eds). Multiple Sclerosis. Philadelphia: FA Davis Company; 1998. 3. Duqette P, Murray TJ, Pleines J et al. Multiple sclerosis in childhood: Clinical profile in 125 patients. Journal of Paediatrics 1987;111:359-363 4. Cottrell DA, Kremenchutzky M, Rice GP et al. The natural history of Multiple Sclerosis: a geographically based study. 5. The clinical features and natural history of primary-progressive Multiple Sclerosis. Brain 1999; 122: 625―39. 5. Weinshenker BG, Rice GP, Noseworthy JH et al. The natural history of Multiple Sclerosis: a geographically6based study. 3. Multivariate analysis of predictive factors and models of outcome. Brain1991; 114: 1045―56. 6. Kurtzke JF. Multiple sclerosis in time and space – geographic clues to cause. J Neurovirol 2000; 6 (suppl 2): S134–40. 7. Dean G, Elian M. Age at immigration to England of Asian and Caribbeanimmigrants and the risk of developing Multiple Sclerosis. J Neurol Neurosurg Psychiatry 1997; 63: 565–8. Kurtzke JF. Multiple sclerosis in time and space – geographic clues to cause. J Neurovirol 2000; 6 (suppl 2): S134–40. 8. Rothwell PM, Charlton D. High incidence and prevalence of Multiple Sclerosis in Southeast Scotland: evidence of a genetic predisposition. J Neurol Neurosurg Psychiatry 1998; 64: 730―5.